Another Side Effect Of Obesity : Cancer

Obesity is a major PREVENTABLE cause of cancer. Major studies confirm that being overweight or obese increases the risk of various cancers.The World Health Organisation (WHO) has stated that, nest to tobacco, overweight and obesity are the most important known avoidable causes of cancer.

It is one of many ill effects of obesity, women who are overweight are more prone to getting cancer when compared to women of normal weight.

Studies conducted show that 68 percent of U.S. adults age 20 years and older are overweight or obese.

One study, using NCI Surveillance, Epidemiology, and End Results (SEER) data, estimated that in 2007 in the United States, about 34,000 new cases of cancer in men (4 percent) and 50,500 in women (7 percent) were due to obesity.

Several factors have shown the relationship between obesity and cancer :

  • Fat tissue produces excess amounts of estrogen, high levels of which have been associated with the risk of breast, endometrial, and some other cancers.
  • Obese people often have increased levels of insulin andinsulin-like growth factor-1 (IGF-1) in their blood (a condition known as hyperinsulinemia or insulin resistance), which may promote the development of certain tumors.
  • Fat cells produce hormones, called adipokines, that may stimulate or inhibit cell growth. For example, leptin, which is more abundant in obese people, seems to promote cell proliferation, whereas adiponectin, which is less abundant in obese people, may have antiproliferative effects.
  • Fat cells may also have direct and indirect effects on other tumor growth regulators, includingmammalian target of rapamycin (mTOR) and AMP-activated protein kinase.
  • Obese people often have chronic low-level, or “subacute,” inflammation, which has been associated with increased cancer risk.

Ladies another very important reason to control your diet.

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