Study, Aspirin Resistance Is a Precursor to Stroke

Aspirin has been considered as the go to drugs when you have a headache, colds, coughs and any illnesses which you’re not even sure of. Just like antibiotics, aspirins may have been over used. A new research study suggests that taking too much aspirin may develop resistance to it. Health wise, it’s risky to develop such condition.

“Aspirin resistance is an important predictor of severe stroke and large stroke size in patients taking aspirin before having a stroke,” Mi Sun Oh, MD, from the department of neurology at the Hallym University College of Medicine in Seoul, South Korea. The lead study author goes on to say, “In patients at high risk for stroke with aspirin resistance, different anti-clotting drugs — such as clopidogrel (Plavix) — can be considered as alternatives to prevent another stroke or decrease stroke severity.”
Oh goes on to say, “Eventually we may be able to identify people who are likely to be resistant to aspirin and give them higher doses or different drugs to prevent blood clots. However, we need better ways to identify people with aspirin resistance before any changes can be made. For now, people who are taking low-dose aspirin to prevent blood clotting and stroke should continue to do so.”

University of Miami Miller School of Medicine chairman of neurology Dr. Ralph Sacco said that this research reveals this aspirin-stroke relationship. He contemplates, “One way aspirin works is to prevent platelets [particles that form clots in the blood] from clumping, and this could mean that clots that are released and block brain arteries are smaller and lead to smaller areas of brain injury.”

Sacco continues, “Although we do not routinely test for aspirin resistance, in the future era of targeted medicine we may improve the ability to assess whether someone is aspirin-resistant and choose medicines more accurately.”



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