A women who had been treated with a super bug infection through a stool transplant from an obese donor had reportedly become increasingly obese herself after the treatment.
A treatment known to effectively counter the bacteria of the so called C. difficile infection requires the patient to undergo a stool transplant procedure that is called Fecal microbiota transplant (FMT) . The infection causes digestive infection and patients who take antibiotics had reportedly experienced dangerous and more serious complications.
The purpose of the fecal transplant procedure is to restore good bacteria that has been destroyed to balance the bad bacteria of the C. difficile bacteria which is increasing and multiplying in the colon. Yet in this case report said that suggestions of being careful in chosing a stool donor should be considered especially those who have over weight problems since it may affect the health of the patient.
The woman patient was said to formerly have good statistics in 2011 at a regular weight and body mass index. The stool that was transplanted was from the woman’s daughter who is overweight but is a healthy teenage girl. The procedure was done through colonoscopy to cure the infection.
After 16 months, there was an increase of weight on the woman from 9.5 stone to a 12 and that her BMI from 26 to 33 which the doctors consider as obesity. She was placed in closely supervised special protein diet and exercise yet her weight did not change. In three years her weight increased more to 12 ½ stone and her BMI to 34.5. This had created a stir among the specialists at the Warren Alpert Medical School of Brown University. : ‘We’re questioning whether there was something in the fecal transplant, whether some of those “good” bacteria we transferred may have had an impact on her metabolism in a negative way.’
This was compared to past animal studies which resulted to a very similar case. The authors of the report had suggested that they select donors who are not overweight. Yet specialists still believe that there are still possibilities that this may not just the only cause of the patient’s gain in weight. The patient also had been treated for her Helicobacter pylori infection with antibiotics.
‘Ultimately, of course, it is hoped that FMT studies will lead to identification of defined mixtures of beneficial bacteria that can be cultured, manufactured, and administered to improve human health.’